Update on the adaptive immune responses of the dental pulp

被引：82

作者：

Hahn, Chin-Lo ^{[1
]}

Liewehr, Frederick R. ^{[1
]}

机构：

[1] Virginia Commonwealth Univ, Dept Endodont, Sch Dent, Richmond, VA 23298 USA

来源：

JOURNAL OF ENDODONTICS | 2007年 / 33卷 / 07期

关键词：

adaptive immunity; caries; chemokines; cytokines; dental pulp; MATURE DENDRITIC CELLS; REGULATORY T-CELLS; MONOCYTE CHEMOTACTIC PROTEIN-1; INTERLEUKIN-8; GENE-EXPRESSION; PERIODONTALLY DISEASED SITES; KAPPA-B ACTIVATION; RAT INCISOR PULP; IN-VIVO; DIFFERENTIAL EXPRESSION; INFLAMMATORY REACTIONS;

D O I：

10.1016/j.joen.2007.01.002

中图分类号：

R78 [口腔科学];

学科分类号：

1003 ;

摘要：

Recent advances in immunology have disclosed the enormous complexity of the immune regulatory system. The dental pulp is equipped to mount adaptive immune responses to caries, which include at least antigen-presenting cells, lymphocytes, mast cells and their cytokines, and chemokines. The purpose of this review is to summarize our current understanding of the roles of these cellular and molecular components in the irreversibly inflamed pulp. The immunopathology of abscess formation and the mechanisms for painless pulpitis are also discussed.

引用

页码：773 / 781

页数：9

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