Highly enantioselective allylation of aldehydes catalyzed by indium(III)-PYBOX complex

被引：75

作者：

Lu, J

Ji, SJ

Teo, YC

Loh, TP

机构：

[1] Natl Univ Singapore, Dept Chem, Singapore 117543, Singapore

[2] Suzhou Univ, Coll Chem & Chem Engn, Key Lab Organ Synth Jiangsu Province, Suzhou 215006, Peoples R China

来源：

ORGANIC LETTERS | 2005年 / 7卷 / 01期

关键词：

D O I：

10.1021/ol047711c

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A chiral indium(III)-PYBOX complex prepared from indium triflate and chiral PYBOX has been discovered to effect high enantioselectivities in the addition of allyltributyl stannane to aldehydes. The allylation of a variety of aromatic, alpha,beta-unsaturated, and aliphatic aldehydes resulted in good yields and high enantioselectivities (up to 94% ee).

引用

页码：159 / 161

页数：3

共 35 条

[31] ACYCLIC STEREOCONTROL VIA ALLYLIC ORGANOMETALLIC COMPOUNDS [J].