High affinity not in the vicinity?

被引：65

作者：

Barker, Philip A. ^{[1
]}

机构：

[1] McGill Univ, Montreal Neurol Inst, Ctr Neuronal Survival, Montreal, PQ H3A 2B4, Canada

来源：

NEURON | 2007年 / 53卷 / 01期

关键词：

D O I：

10.1016/j.neuron.2006.12.018

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Functional interactions between the p75 neurotrophin receptor (p75NTR) and the Trk receptors were demonstrated several years ago, but their mechanistic basis remains uncertain. In this issue of Neuron, Wehrman et al. provide a three-dimensional structure of the full TrkA ectodomain complexed to NGF and examine the possibility of a ternary p75NTR-NGF-TrkA complex.

引用

页码：1 / 4

页数：4

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