Mechanochemical crosstalk during endocytic vesicle formation

被引:48
作者
Liu, Jian [1 ]
Sun, Yidi [1 ]
Oster, George F. [1 ]
Drubin, David G. [1 ]
机构
[1] Univ Calif Berkeley, Dept Mol & Cell Biol, Berkeley, CA 94720 USA
基金
美国国家科学基金会;
关键词
N-BAR DOMAIN; MEMBRANE CURVATURE; LIPID RAFTS; MEDIATED ENDOCYTOSIS; LATERAL ORGANIZATION; LINE TENSION; COATED PITS; ACTIN; CLATHRIN; DYNAMIN;
D O I
10.1016/j.ceb.2009.11.009
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
Membrane curvature has emerged as a key regulatory factor in endocytic vesicle formation. From a theoretical perspective, we summarize recent progress in understanding how membrane curvature and biochemical pathways are coupled and orchestrated during the coherent process of endocytic vesicle formation. We mainly focus on clathrin-mediated and actin-mediated endocytosis in yeast and in mammalian cells. We further speculate on how mechanochemical feedback could modulate other membrane-remodeling processes.
引用
收藏
页码:36 / 43
页数:8
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