The role of chromatin in HIV-1 transcriptional regulation

被引：10

作者：

Mirkovitch, J ^{[1
]}

机构：

[1] Swiss Inst Expt Canc Res, ISREC, CH-1066 Epalinges, Switzerland

来源：

IMMUNOBIOLOGY | 1997年 / 198卷 / 1-3期

关键词：

D O I：

10.1016/S0171-2985(97)80048-4

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Regulation of transcription is a key feature of the HIV-1 life cycle. In recent years, various sequence elements and transcription factors have been shown to participate in HIV-1 transcription control. New evidence, however, has shown that chromatin organization plays a key role in the establishment of a transcriptionally regulated HIV-1 LTR. The present review discusses recent data obtained on reconstituted and genomic HIV-1 chromatin templates.

引用

页码：279 / 290

页数：12

共 65 条

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