共 21 条
Preparation and application of a molecularly imprinted polymer for the determination of trace metolcarb in food matrices by high performance liquid chromatography
被引:24
作者:
Qian, Kun
[1
]
Fang, Guozhen
[1
]
He, Jinxing
[1
]
Pan, Mingfei
[1
]
Wang, Shuo
[1
]
机构:
[1] Tianjin Univ Sci & Technol, Minist Educ, Key Lab Food Nutr & Safety, Tianjin 300457, Peoples R China
基金:
中国国家自然科学基金;
关键词:
Food matrices;
Metolcarb;
Molecularly imprinted polymer;
SPE;
SOLID-PHASE EXTRACTION;
FLUORESCENCE DETECTION;
MASS-SPECTROMETRY;
PESTICIDES;
CARBAMATE;
WATER;
D O I:
10.1002/jssc.200900877
中图分类号:
O65 [分析化学];
学科分类号:
070302 ;
081704 ;
摘要:
In this article, for the first time, a molecularly imprinted polymer (MIP) for the metolcarb was prepared by bulk polymerization using metolcarb as the template, methacrylic acid as the functional monomer and ethylene glycol dimethacrylate as the cross-linker. The prepared polymer was characterized by FT-IR, static and kinetic adsorption experiments, and the results showed that it has been successfully synthesized and had good selective ability for metolcarb. The MIP was applied as a sorbent in molecularly imprinted SPE coupled with HPLC-UV for separation and determination of trace metolcarb in three kinds of food matrices at three concentration levels. Under the optimal conditions, the LODs (S/N = 3) of cabbage, cucumber and pear were 7.622, 6.455 and 13.52 mu g/kg, respectively, and recoveries were in the range of 68.80-101.31% with RSD (n = 3) below 3.78% in all cases. To demonstrate further the selectivity of the MIP obtained, a comparison with commercially available C-18 SPE was performed. The results indicated that molecularly imprinted SPE showed better chromatography, better selectivity and higher recoveries for metolcarb than commercially available C-18 SPE.
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页码:2079 / 2085
页数:7
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