SCANMS: adjusting for multiple comparisons in sliding window neutrality tests

被引：9

作者：

Ardell, DH ^{[1
]}

机构：

[1] Uppsala Univ, Biomed Ctr, Dept Cell & Mol Biol, SE-75124 Uppsala, Sweden

来源：

BIOINFORMATICS | 2004年 / 20卷 / 12期

关键词：

D O I：

10.1093/bioinformatics/bth187

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

A Perl utility called SCANMS was written that operates on parametric bootstrap data generated by Hudson's simulator MS. SCANMS simulates sliding window analysis of Tajima's D or Fu and Li's D-* or F-* over the replicates and generates the empirical joint distribution of window minima and maxima. This distribution may then be used to calculate achieved significance values or significance cutoffs that account for multiple comparisons in sliding window analysis of real data.

引用

页码：1986 / 1988

页数：3

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