Cyclization of aromatic polyketides from bacteria and fungi

被引:104
作者
Zhou, Hui [1 ]
Li, Yanran [1 ]
Tang, Yi [1 ]
机构
[1] Univ Calif Los Angeles, Dept Chem & Biomol Engn, Los Angeles, CA 90095 USA
基金
美国国家科学基金会; 美国国家卫生研究院;
关键词
BIOSYNTHETIC GENE-CLUSTER; I FATTY-ACID; MALONYL-COENZYME-A; ENGINEERED BIOSYNTHESIS; HETEROLOGOUS EXPRESSION; SYNTHASE GENES; CRYSTAL-STRUCTURE; ENZYMATIC-SYNTHESIS; STREPTOMYCES-GLAUCESCENS; ASPERGILLUS-NIDULANS;
D O I
10.1039/b911518h
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
This review discusses the enzymatic basis of the different cyclization strategies used by bacteria and fungi in the biosynthesis of aromatic polyketides.
引用
收藏
页码:839 / 868
页数:30
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