RNA silencing in plants

被引:1798
作者
Baulcombe, D [1 ]
机构
[1] John Innes Ctr Plant Sci Res, Sainsbury Lab, Norwich NR4 7UH, Norfolk, England
关键词
D O I
10.1038/nature02874
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
There are at least three RNA silencing pathways for silencing specific genes in plants. In these pathways, silencing signals can be amplified and transmitted between cells, and may even be self-regulated by feedback mechanisms. Diverse biological roles of these pathways have been established, including defence against viruses, regulation of gene expression and the condensation of chromatin into heterochromatin. We are now in a good position to investigate the full extent of this functional diversity in genetic and epigenetic mechanisms of genome control.
引用
收藏
页码:356 / 363
页数:8
相关论文
共 87 条
  • [81] Genetic and functional diversification of small RNA pathways in plants
    Xie, ZX
    Johansen, LK
    Gustafson, AM
    Kasschau, KD
    Lellis, AD
    Zilberman, D
    Jacobsen, SE
    Carrington, JC
    [J]. PLOS BIOLOGY, 2004, 2 (05) : 642 - 652
  • [82] Negative feedback regulation of Dicer-Like1 in Arabidopsis by microRNA-guided mRNA degradation
    Xie, ZX
    Kasschau, KD
    Carrington, JC
    [J]. CURRENT BIOLOGY, 2003, 13 (09) : 784 - 789
  • [83] An important role of an inducible RNA-dependent RNA polymerase in plant antiviral defense
    Xie, ZX
    Fan, BF
    Chen, CH
    Chen, ZX
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2001, 98 (11) : 6516 - 6521
  • [84] Empirical analysis of transcriptional activity in the Arabidopsis genome
    Yamada, K
    Lim, J
    Dale, JM
    Chen, HM
    Shinn, P
    Palm, CJ
    Southwick, AM
    Wu, HC
    Kim, C
    Nguyen, M
    Pham, P
    Cheuk, R
    Karlin-Newmann, G
    Liu, SX
    Lam, B
    Sakano, H
    Wu, T
    Yu, GX
    Miranda, M
    Quach, HL
    Tripp, M
    Chang, CH
    Lee, JM
    Toriumi, M
    Chan, MMH
    Tang, CC
    Onodera, CS
    Deng, JM
    Akiyama, K
    Ansari, Y
    Arakawa, T
    Banh, J
    Banno, F
    Bowser, L
    Brooks, S
    Carninci, P
    Chao, QM
    Choy, N
    Enju, A
    Goldsmith, AD
    Gurjal, M
    Hansen, NF
    Hayashizaki, Y
    Johnson-Hopson, C
    Hsuan, VW
    Iida, K
    Karnes, M
    Khan, S
    Koesema, E
    Ishida, J
    [J]. SCIENCE, 2003, 302 (5646) : 842 - 846
  • [85] Recognition of small interfering RNA by a viral suppressor of RNA silencing
    Ye, KQ
    Malinina, L
    Patel, DJ
    [J]. NATURE, 2003, 426 (6968) : 874 - 878
  • [86] A systemic small RNA signaling system in plants
    Yoo, BC
    Kragler, F
    Varkonyi-Gasic, E
    Haywood, V
    Archer-Evans, S
    Lee, YM
    Lough, TJ
    Lucas, WJ
    [J]. PLANT CELL, 2004, 16 (08) : 1979 - 2000
  • [87] ARGONAUTE4 control of locus-specific siRNA accumulation and DNA and histone methylation
    Zilberman, D
    Cao, XF
    Jacobsen, SE
    [J]. SCIENCE, 2003, 299 (5607) : 716 - 719