High probability perfusion lung scans in pulmonary venoocclusive disease

被引:67
作者
Bailey, CL [1 ]
Channick, RN [1 ]
Auger, WR [1 ]
Fedullo, PF [1 ]
Kerr, KM [1 ]
Yung, GL [1 ]
Rubin, LJ [1 ]
机构
[1] Univ Calif San Diego, Sch Med, Med Ctr, Div Pulm & Crit Care Med, San Diego, CA 92103 USA
关键词
D O I
10.1164/ajrccm.162.5.2003045
中图分类号
R4 [临床医学];
学科分类号
1002 ; 100602 ;
摘要
High-probability ventilation/perfusion (((V) over dot/(Q) over dot)) lung scans generally indicate proximal pulmonary arterial occlusion by thromboemboli or, rarely, other processes such as tumors, fibrosing mediastinitis, or vasculitis. In this report we describe three patients with high probability (V) over dot/(Q) over dot scans in whom pulmonary angiography failed to demonstrate arterial occlusion. All three patients were determined to have pulmonary venoocclusive disease (PVOD). In two patients, a tissue diagnosis of PVOD was made, in one case with explanted tissue taken after a successful heart-lung transplant and in the other case with tissue taken at autopsy. PVOD in the third patient was diagnosed with pulmonary venography. A potential explanation for the discrepancy between perfusion lung scan and pulmonary angiographic findings in PVOD is discussed.
引用
收藏
页码:1974 / 1978
页数:5
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