Tolerance to the Foetal Allograft?

被引:57
作者
Chaouat, Gerard [1 ]
Petitbarat, Marie
Dubanchet, Sylvie
Rahmati, Mona
Ledee, Nathalie
机构
[1] Univ Paris 11, INSERM, U782, F-92141 Clamart, France
关键词
Conceptus; placenta; pregnancy; tolerance; REGULATORY T-CELLS; MURINE TROPHOBLAST; TRANSPLANTATION IMMUNITY; PATERNAL ALLOANTIGENS; IMMUNOACTIVE PRODUCTS; SPONTANEOUS-ABORTION; MEDIATED LYSIS; PREGNANT-WOMEN; NK CELLS; RESISTANCE;
D O I
10.1111/j.1600-0897.2010.00832.x
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
In this review, we will detail the concept of tolerance and its history in reproductive immunology. We will then consider whether it applies to the foetal-maternal relationship and discuss the mechanisms involved in non-rejection of the foeto-placental unit.
引用
收藏
页码:624 / 636
页数:13
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