New palladium(II)-catalyzed asymmetric 1,2-dibromo synthesis

被引：78

作者：

El-Qisairi, AK ^{[1
]}

Qaseer, HA ^{[1
]}

Katsigras, G ^{[1
]}

Lorenzi, P ^{[1
]}

Trivedi, U ^{[1
]}

Tracz, S ^{[1
]}

Hartman, A ^{[1
]}

Miller, JA ^{[1
]}

Henry, PM ^{[1
]}

机构：

[1] Loyola Univ, Dept Chem, Chicago, IL 60626 USA

来源：

ORGANIC LETTERS | 2003年 / 5卷 / 04期

关键词：

D O I：

10.1021/ol0273093

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

[GRAPHICS] The oxidation of olefins by chiral monometallic and bimetallic Pd(II)-Cu(II) catalysts in bromide-containing aqueous-THF reaction mixtures produced chiral 1,2-dibromides. With alpha-olefins, the ee's were about 95% while most of the internal alkenes gave somewhat lower enantioselectivities (similar to80%).

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页码：439 / 441

页数：3

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