Synthesis and biological evaluation of dehydroabietic acid derivatives

被引：107

作者：

Gonzalez, Miguel A. ^{[1
]}

Perez-Guaita, David ^{[1
]}

Correa-Royero, Julieth ^{[2
]}

Zapata, Bibiana ^{[2
]}

Agudelo, Lee ^{[2
]}

Mesa-Arango, Ana ^{[2
]}

Betancur-Galvis, Liliana ^{[2
]}

机构：

[1] Univ Valencia, Dept Quim Organ, E-46100 Valencia, Spain

[2] Univ Antioquia, Grp Bioactividad, Fac Med, Medellin 1226, Colombia

来源：

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY | 2010年 / 45卷 / 02期

关键词：

Abietic acid; Dehydroabietic acid; Cytotoxicity; Antimycotic activity; Antiviral activity; ABIETIC ACID; CYTOTOXIC ACTIVITY; DITERPENOIDS; CONSTITUENTS; OXIDATION; LEAVES;

D O I：

10.1016/j.ejmech.2009.10.010

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

A series of C18-oxygenated derivatives of dehydroabietic acid were synthesized from commercial abietic acid and evaluated for their cytotoxic, antimycotic, and antiviral activities. (C) 2009 Elsevier Masson SAS. All rights reserved.

引用

页码：811 / 816

页数：6

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