17q12-21 variants interact with smoke exposure as a risk factor for pediatric asthma but are equally associated with early-onset versus late-onset asthma in North Americans of European ancestry

被引:72
作者
Flory, James H. [1 ]
Sleiman, Patrick M. [1 ]
Christie, Jason D. [6 ]
Annaiah, Kiran [1 ]
Bradfield, Jonathan [1 ]
Kim, Cecilia E. [1 ]
Glessner, Joseph [1 ]
Imielinski, Marcin [1 ]
Li, Hongzhe [1 ]
Frackelton, Edward C. [1 ]
Hou Cuiping [1 ]
Otieno, George [1 ]
Thomas, Kelly [1 ]
Smith, Ryan [1 ]
Glaberson, Wendy [1 ]
Garris, Maria [1 ]
Chiavacci, Rosetta [1 ]
Allen, Julian [2 ]
Spergel, Jonathan [3 ]
Grundmeier, Robert [4 ]
Grunstein, Michael [2 ]
Magnusson, Michael [5 ]
Grant, Struan F. A. [1 ]
Bonnelykke, Klaus [7 ]
Bisgaard, Hans [7 ]
Hakonarson, Hakon [1 ]
机构
[1] Childrens Hosp Philadelphia, Ctr Appl Genom, Philadelphia, PA 19104 USA
[2] Childrens Hosp Philadelphia, Div Pulm Med, Philadelphia, PA 19104 USA
[3] Childrens Hosp Philadelphia, Div Allergy & Immunol, Philadelphia, PA 19104 USA
[4] Childrens Hosp Philadelphia, Dept Bioinformat, Philadelphia, PA 19104 USA
[5] Childrens Hosp Philadelphia, Dept Pediat, Philadelphia, PA 19104 USA
[6] Univ Penn, Dept Med, Ctr Clin Epidemiol & Biostat, Philadelphia, PA 19104 USA
[7] Univ Copenhagen, Dept Hlth Sci, Copenhagen, Denmark
关键词
GENE;
D O I
10.1016/j.jaci.2009.05.047
中图分类号
R392 [医学免疫学];
学科分类号
100102 ;
摘要
引用
收藏
页码:605 / 607
页数:4
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