Multilocus sequence typing (MLST) of Escherichia coli O78 strains

被引：48

作者：

Adiri, RS ^{[1
]}

Gophna, U ^{[1
]}

Ron, EZ ^{[1
]}

机构：

[1] Tel Aviv Univ, Dept Mol Microbiol & Biotechnol, Fac Life Sci, IL-69978 Tel Aviv, Israel

来源：

FEMS MICROBIOLOGY LETTERS | 2003年 / 222卷 / 02期

关键词：

multilocus sequence typing; bacterial virulence; serotype O78; sepsis; avian colisepticemia; newborn meningitis;

D O I：

10.1016/S0378-1097(03)00295-7

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Strains of Escherichia coli serotype O78 are associated with many diseases, including invasive infections, in humans and farm animals. The clonal relationship between strains from different hosts is therefore important for assessing the risk of zoonotic infections. Here we propose a multilocus sequence typing scheme for E coli, based on six housekeeping genes. Preliminary, but significant, results indicate that clonal division in E coli O78 strains is host independent, and closely related clones reside in different hosts. There was a positive correlation between virulence and clonal origin. (C) 2003 Federation of European Microbiological Societies. Published by Elsevier Science B.V. All rights reserved.

引用

页码：199 / 203

页数：5

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