Manufacturing and standardizing allergen vaccines

被引：3

作者：

Larsen, JN ^{[1
]}

Lowenstein, H ^{[1
]}

机构：

[1] ALK Abello AS, DK-2970 Horsholm, Denmark

来源：

IMMUNOLOGY AND ALLERGY CLINICS OF NORTH AMERICA | 2000年 / 20卷 / 03期

关键词：

D O I：

10.1016/S0889-8561(05)70169-7

中图分类号：

R392 [医学免疫学];

学科分类号：

100102 ;

摘要：

Allergen vaccines are complex biologic mixtures in which standardization is essential to ensure efficacy and safety in allergic diagnosis and therapy. Statistically, a patient's IgE will bind to some allergens more frequently than others, thereby defining major allergens. All allergens are proteins and all soluble proteins are potential allergens. For major allergens, micrograms are the useable measure for optimal clinical maintenance doses. Recombinant allergens are likely to replace natural allergens in the future.

引用

页码：609 / +

页数：16

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