Improved synthesis of N-alkyl substituted dithieno[3,2-b:2′,3′-d]pyrroles

被引：61

作者：

Koeckelberghs, G

De Cremer, L

Vanormelingen, W

Dehaen, W

Verbiest, T

Persoons, A

Samyn, C

机构：

[1] Katholieke Univ Leuven, Lab Macromol & Phys Organ Chem, B-3001 Heverlee, Belgium

[2] Katholieke Univ Leuven, Lab Chem & Biol Dynam, B-3001 Heverlee, Belgium

[3] Katholieke Univ Leuven, Synth Organ Lab, B-3001 Heverlee, Belgium

来源：

TETRAHEDRON | 2005年 / 61卷 / 03期

关键词：

D O I：

10.1016/j.tet.2004.10.106

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A new, convergent and improved synthetic method to prepare N-alkyl substituted dithienopyrroles is described. The procedure consists of a Pd-catalyzed amination of 3,3'-dibromo-2,2'-bithiophene. The reaction conditions were optimized, which makes this method applicable to prepare these molecules easily in high yields and on a large scale. (C) 2004 Elsevier Ltd. All rights reserved.

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页码：687 / 691

页数：5

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