Angiogenesis inhibitors in the treatment of small cell and non-small cell lung cancer

被引：12

作者：

Blackhall, FH

Shepherd, FA

机构：

[1] Princess Margaret Hosp, Toronto, ON M5G 2M9, Canada

[2] Christie Hosp NHS Trust, Dept Med Oncol, Manchester M20 4BX, Lancs, England

[3] Univ Toronto, Toronto, ON M5G 2M9, Canada

来源：

HEMATOLOGY-ONCOLOGY CLINICS OF NORTH AMERICA | 2004年 / 18卷 / 05期

关键词：

D O I：

10.1016/j.hoc.2004.06.005

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Angiogenesis is believed to play a critical role in cancer; however, antiangiogenic therapy has not been demonstrated to improve the survival of patients who have lung cancer. In this article, the evidence that supports a role for angiogenesis in the pathogenesis of lung cancer, trials of antiangiogenic agents in lung cancer performed to date, and the lessons learned from these studies are discussed.

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页码：1121 / +

页数：22

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