Facile preparation of complex protein architectures with sub-100-nm resolution on surfaces

被引:85
作者
Coyer, Sean R.
Garcia, Andres J.
Delamarche, Emmanuel [1 ]
机构
[1] IBM Res GmbH, Zurich Res Lab, CH-8803 Ruschlikon, Switzerland
[2] Georgia Inst Technol, Petit Inst Bioengn & Biosci, George W Woodruff Sch Mech Engn, Atlanta, GA 30332 USA
关键词
lithography; nanotechnology; proteins; scanning probe microscopy; surface analysis;
D O I
10.1002/anie.200700989
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
(Figure Presented) Ink, subtract, print: A novel method is developed for patterning proteins into complex architectures with high resolution, high contrast, and self-alignment (see fluorescence micrographs). An elastomer is inked with proteins, and a nanotemplate is used to selectively subtract proteins, leaving a pattern that is then printed onto a substrate. © 2007 Wiley-VCH Verlag GmbH & Co. KGaA.
引用
收藏
页码:6837 / 6840
页数:4
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