Zoonotic aspects of rotaviruses

被引：438

作者：

Martella, V. ^{[1
]}

Banyai, Krisztian ^{[2
]}

Matthijnssens, Jelle ^{[3
]}

Buonavoglia, Canio ^{[1
]}

Ciarlet, Max ^{[4
]}

机构：

[1] Univ Bari, Dept Vet Publ Hlth, I-70010 Bari, Italy

[2] Hungarian Acad Sci, Vet Med Res Inst, H-1581 Budapest, Hungary

[3] Univ Louvain, Dept Microbiol & Immunol, Rega Inst Med Res, Louvain, Belgium

[4] Merck Res Labs, N Wales, PA USA

来源：

VETERINARY MICROBIOLOGY | 2010年 / 140卷 / 3-4期

基金：

匈牙利科学研究基金会;

关键词：

Rotaviruses; Zoonoses; GROUP-C ROTAVIRUSES; GROUP-A ROTAVIRUSES; MOLECULAR CHARACTERIZATION; AVIAN ROTAVIRUS; GROUP-B; GENETIC-HETEROGENEITY; CLOSE RELATIONSHIP; PROVIDES EVIDENCE; RHESUS ROTAVIRUS; ACUTE DIARRHEA;

D O I：

10.1016/j.vetmic.2009.08.028

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Rotaviruses are important enteric pathogens of humans and animals. Group A rotaviruses (GARVs) account for up to 1 million children deaths each year, chiefly in developing countries and human vaccines are now available in many countries. Rotavirus-associated enteritis is a major problem in livestock animals, notably in young calves and piglets. Early in the epidemiological GARV studies in humans, either sporadic cases or epidemics by atypical, animal-like GARV strains were described. Complete genome sequencing of human and animal GARV strains has revealed a striking genetic heterogeneity in the 11 double stranded RNA segments across different rotavirus strains and has provided evidence for frequent intersections between the evolution of human and animal rotaviruses, as a result of multiple, repeated events of interspecies transmission and subsequent adaptation. (C) 2009 Elsevier B.V. All rights reserved.

引用

页码：246 / 255

页数：10

共 93 条

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