Enantiomer separations on chiral stationary phases in supercritical fluid chromatography

被引：68

作者：

Williams, KL

Sander, LC

机构：

[1] Analytical Chemistry Division, Chem. Sci. and Technology Laboratory, Natl. Inst. of Std. and Technology, Gaithersburg

来源：

JOURNAL OF CHROMATOGRAPHY A | 1997年 / 785卷 / 1-2期

关键词：

enantiomer separation; chiral stationary phases; SFC; reviews;

D O I：

10.1016/S0021-9673(97)00575-X

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Supercritical fluid chromatography (SFC) has proven to be widely applicable fcr the separation of enantiomers on chiral stationary phases. Many of the chiral selectors utilized in gas and liquid chromatography have also been transferred to SFC. This article provides an overview of the types of separations reported on different classes of chiral stationary phases in SFC and includes comparisons of SFC to other chromatographic techniques. The importance of various chromatographic parameters in obtaining successful enantioseparations in SFC is also discussed. (C) 1997 Elsevier Science B.V.

引用

页码：149 / 158

页数：10

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