Cellular expression of the cytolytic factor in earthworms Eisenia foetida

被引：43

作者：

Bilej, M

Rossmann, P

Sinkora, M

Hanusová, R

Beschin, A

Raes, G

De Baetselier, P

机构：

[1] Acad Sci Czech Republ, Inst Microbiol, Dept Immunol, CR-14220 Prague 4, Czech Republic

[2] Charles Univ Prague, Fac Sci, Prague 2, Czech Republic

[3] Free Univ Brussels VIB, Unit Cellular Immunol, B-1640 Rhode St Genese, Belgium

来源：

IMMUNOLOGY LETTERS | 1998年 / 60卷 / 01期

关键词：

Eisenia foetida; coelomic fluid; coelomic cytolytic factor 1 (CCF-1); lipopolysaccharide; TNF; coelomocytes; chloragogenous tissue;

D O I：

10.1016/S0165-2478(97)00127-2

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Coelomic fluid of earthworms contains a 42 kDa protein designated CCF-1 (coelomic cytolytic factor 1), which accounts for approximately 40% of cytolytic activity of the entire coelomic fluid. CCF-1 was documented to be present on cells of the mesenchymal lining of the coelomic cavity as well as on free coelomocytes. Both cellular and humoral levels of CCF-1 were significantly increased after parenteral injection of endotoxin. Moreover, CCF-1 seems to be involved in cell mediated cytotoxicity, because cytotoxic activity is blocked in the presence of anti-CCF-1 monoclonal antibody (mAb). (C) 1998 Elsevier Science B.V.

引用

页码：23 / 29

页数：7

共 38 条

[1] CHARACTERIZATION OF INTERLEUKIN-1 ACTIVITY IN TUNICATES
BECK, G
VASTA, GR
MARCHALONIS, JJ
HABICHT, GS
[J]. COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY, 1989, 92 (01): : 93 - 98
[2] PURIFICATION AND BIOCHEMICAL-CHARACTERIZATION OF AN INVERTEBRATE INTERLEUKIN-1
BECK, G
HABICHT, GS
[J]. MOLECULAR IMMUNOLOGY, 1991, 28 (06) : 577 - 584
[3] INVERTEBRATE CYTOKINES .3. INVERTEBRATE INTERLEUKIN-1-LIKE MOLECULES STIMULATE PHAGOCYTOSIS BY TUNICATE AND ECHINODERM CELLS
BECK, G
OBRIEN, RF
HABICHT, GS
STILLMAN, DL
COOPER, EL
RAFTOS, DA
[J]. CELLULAR IMMUNOLOGY, 1993, 146 (02) : 284 - 299
[4] PRIMITIVE CYTOKINES - HARBINGERS OF VERTEBRATE DEFENSE
BECK, G
HABICHT, GS
[J]. IMMUNOLOGY TODAY, 1991, 12 (06): : 180 - 183
[5] ISOLATION AND CHARACTERIZATION OF A PRIMITIVE INTERLEUKIN-1-LIKE PROTEIN FROM AN INVERTEBRATE, ASTERIAS-FORBESI
BECK, G
HABICHT, GS
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1986, 83 (19) : 7429 - 7433
[6] BECK G, 1996, ADV COMP ENV PHYSL, V24, P29
[7] REPEATED ANTIGENIC CHALLENGE INDUCES EARTHWORM CELOMOCYTE PROLIFERATION
BILEJ, M
SIMA, P
SLIPKA, J
[J]. IMMUNOLOGY LETTERS, 1992, 32 (02) : 181 - 184
[8] IDENTIFICATION OF A CYTOLYTIC PROTEIN IN THE CELOMIC FLUID OF EISENIA-FOETIDA EARTHWORMS
BILEJ, M
BRYS, L
BESCHIN, A
LUCAS, R
VERCAUTEREN, E
HANUSOVA, R
DEBAETSELIER, P
[J]. IMMUNOLOGY LETTERS, 1995, 45 (1-2) : 123 - 128
[9] ENDOTOXIN-INDUCED SERUM FACTOR THAT CAUSES NECROSIS OF TUMORS
CARSWELL, EA
OLD, LJ
KASSEL, RL
GREEN, S
FIORE, N
WILLIAMSON, B
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1975, 72 (09) : 3666 - 3670
[10] AUTOGENEIC BUT NOT ALLOGENEIC EARTHWORM EFFECTOR CELOMOCYTES KILL THE MAMMALIAN TUMOR-CELL TARGET K562
COOPER, EL
COSSARIZZA, A
SUZUKI, MM
SALVIOLI, S
CAPRI, M
QUAGLINO, D
FRANCESCHI, C
[J]. CELLULAR IMMUNOLOGY, 1995, 166 (01) : 113 - 122

← 1 2 3 4 →