The efficacy of oral ribavirin in the treatment of Crimean-Congo hemorrhagic fever in Iran

被引：140

作者：

Mardani, M

Jahromi, MK

Naieni, KH

Zeinali, M

机构：

[1] Shahid Beheshti Univ Med Sci, Dept Trop Med & Infect Dis, Tehran, Iran

[2] Univ Tehran Med Sci, Sch Publ Hlth, Dept Epidemiol & Biostat, Tehran, Iran

[3] Minist Hlth & Med Educ, Tehran, Iran

来源：

CLINICAL INFECTIOUS DISEASES | 2003年 / 36卷 / 12期

关键词：

D O I：

10.1086/375058

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

We compared the mortality rate among patients suspected of having Crimean-Congo hemorrhagic fever (CCHF) who received treatment with oral ribavirin and those who did not. Ninety-seven (69.8%) of 139 treated patients suspected of having CCHF survived, and 61 (88.9%) of 69 treated patients with confirmed CCHF survived. The efficacy of oral ribavirin was 80% among patients with confirmed CCHF and 34% among patients suspected of having CCHF. Considering the limitations of observational studies, we conclude that oral ribavirin is an effective treatment for the hemorrhagic form of CCHF.

引用

页码：1613 / 1618

页数：6

共 13 条

[1] The use of a reverse transcription-polymerase chain reaction for the detection of viral nucleic acid in the diagnosis of Crimean-Congo haemorrhagic fever [J].