Distribution of the α7 nicotinic acetylcholine receptor subunit in the developing chick cerebellum

被引：11

作者：

Kaneko, WM

Britto, LRG

Lindstrom, JM

Karten, HJ

机构：

[1] Univ Calif San Diego, Dept Neurosci 0608, La Jolla, CA 92093 USA

[2] Univ Sao Paulo, Inst Biomed Sci, Dept Physiol & Biophys, BR-05508900 Sao Paulo, Brazil

[3] Univ Penn, Dept Neurosci, Philadelphia, PA 19104 USA

来源：

DEVELOPMENTAL BRAIN RESEARCH | 1998年 / 105卷 / 01期

基金：

巴西圣保罗研究基金会;

关键词：

alpha-bungarotoxin; Purkinje cell; granule cell; embryonic; neurotransmitter; development;

D O I：

10.1016/S0165-3806(97)00160-0

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Previous studies of the nicotinic acetylcholine receptor (nAChR) subunits in adult mammalian and avian brains have demonstrated a spatially restricted distribution of these subunits; little, however, is known about the nAChR subunit developmental distribution. The present study demonstrated a transient pattern of distribution of the neuronal nAChR subunit, alpha 7, in the developing chick cerebellum by using immunohistochemical techniques. This transient distribution may suggest a critical period for the development of the cholinergic system in the cerebellum. (C) 1998 Elsevier Science B.V.

引用

收藏

页码：141 / 145

页数：5

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