Association of a functional polymorphism of the monoamine oxidase A gene promoter with personality and psychiatric symptoms

被引：42

作者：

Jorm, AF

Henderson, AS

Jacomb, PA

Christensen, H

Korten, AE

Rodgers, B

Tan, X

Easteal, S

机构：

[1] Australian Natl Univ, Mental Hlth Res Ctr, Canberra, ACT 0200, Australia

[2] Australian Natl Univ, John Curtin Sch Med Res, Canberra, ACT 2601, Australia

来源：

PSYCHIATRIC GENETICS | 2000年 / 10卷 / 02期

关键词：

neuroticism; extraversion; psychoticism; anxiety; depression; alcohol abuse; genetics; monoamine oxidase A;

D O I：

10.1097/00041444-200010020-00006

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

A functional polymorphism in the promoter of the monoamine oxidase gene has recently been described by Sabol et at. This polymorphism is a strong candidate for associations with personality traits and psychiatric symptoms. We report relevant data from a general population sample of 850 Caucasian Australians. We found no associations with anxiety and depression symptoms, with personality traits that predispose to anxiety (neuroticism, behavioral inhibition, negative affect) or to a personality trait related to antisocial behavior (psychoticism). Psychiatr Genet 10:87-90 (C) 2000 Lippincott Williams & Wilkins.

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收藏

页码：87 / 90

页数：4

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