Constituents of aromatic plants: carvacrol

被引:182
作者
De Vincenzi, M [1 ]
Stammati, A
De Vincenzi, A
Silano, M
机构
[1] Ist Super Sanita, Dept Metab & Pathol Biochem, Rome, Italy
[2] Ist Super Sanita, Dept Comparat Toxicol & Ecotoxicol, Rome, Italy
[3] Univ Roma La Sapienza, Rome, Italy
关键词
Thymus capitatus; T; vulgaris; serpyllum; Satureja hortensis; S; montana; Origanum dictamus; O; majorana; carvacrol;
D O I
10.1016/j.fitote.2004.05.002
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
Carvacrol is a component of numerous aromatic plants. Up to now, no toxicological data were available. Carvacrol show a weak activity in the mutagenicity studies. Moreover, in the metabolism study, carvacrol has shown to be excreted with urine after 24 h in large quantities or unchanged or as glucoronide and sulphate conjugates. The available data do not allow the assessment of the NOEL. Further toxicological studies are needed. (C) 2004 Elsevier B.V. All rights reserved.
引用
收藏
页码:801 / 804
页数:4
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