Chemical composition and antimicrobial activity of the essential oil of Cryptomeria japonica

被引：54

作者：

Cha, Jeong-Dan

Jeong, Mi-Ran

Jeong, Seung-Ii

Moon, Sang Eun

Kil, Bong-Seop

Yun, Soon-Il

Lee, Kyung-Yeol

Song, Yo-Han

机构：

[1] Chonbuk Natl Univ, Dept Oral Microbiol, Sch Dent, Jeonju 561756, South Korea

[2] Chonbuk Natl Univ, Inst Oral Biosci, Jeonju 561756, South Korea

[3] Wonkwang Univ, Dept Herbal Resources, Profess Grad Sch Oriental Med, Iksan, South Korea

[4] Inst Jeonju Biomat Inst, Jeonju, South Korea

[5] Wonkwang Univ, Div Life Sci, Coll Nat Sci, Iksan, South Korea

[6] Chonbuk Natl Univ, Div Biotechnol, Jeonju, South Korea

来源：

PHYTOTHERAPY RESEARCH | 2007年 / 21卷 / 03期

关键词：

Cryptomeria japonica; essential oil; GC/MS; antimicrobial activity;

D O I：

10.1002/ptr.1864

中图分类号：

R914 [药物化学];

学科分类号：

100701 [药物化学];

摘要：

The composition and the antibacterial activity of the essential oil obtained from Cryptomeria japonica D. Don on oral bacteria were studied. The chemical composition of the essential oil was analysed by GC and GC-MS. Sixty-eight compounds accounting for 95.82% of the oil were identified. The main compounds in the oil were alpha-pinene (6.07%), sabinene (8.86%), terpinen-4-oL (9.77%), alpha-terpineol (6.13%), elemol (11.17%) and 10(15)-cadinen-4-oL (7.16%). The essential oil and some of its major compounds were tested for antimicrobial activity against 15 different genera of oral bacteria. The essential oil of C. japonica exhibited considerable inhibitory effects against all bacteria tested (MICs, 0.025-0.05 mg/mL; MBCs, 0.025-0.1 mg/mL), while its major compounds demonstrated various degrees of growth inhibition. Copyright (c) 2007 John Wiley & Sons, Ltd.

引用

页码：295 / 299

页数：5

共 12 条

[1]

Three new sesquiterpenes from the black heartwood of Cryptomeria japonica [J].