Genetic heterogeneity of autoimmune disorders in the nonobese diabetic mouse

被引:18
作者
Johansson, ÅCM [1 ]
Lindqvist, AKB [1 ]
Johannesson, M [1 ]
Holmdahl, R [1 ]
机构
[1] Lund Univ, Dept Cell & Mol Biol, Sect Med Inflammat Res L11, BMC, SE-22184 Lund, Sweden
关键词
D O I
10.1046/j.1365-3083.2003.01235.x
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
The nonobese diabetic mouse is highly susceptible not only to diabetes but to several autoimmune diseases, and one might suspect that these are controlled by a shared set of genes. However, based on various gene-segregation experiments, it seems that only a few loci are shared and that each disorder is influenced also by a unique set of genes.
引用
收藏
页码:203 / 213
页数:11
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