Short synthesis of functionalized pentalongin derivatives using pyridinium ylid chemistry

被引：6

作者：

Claes, Pieter ^{[1
]}

Jacobs, Jan ^{[1
]}

Claessens, Sven ^{[1
]}

De Kimpe, Norbert ^{[1
]}

机构：

[1] Univ Ghent, Fac Biosci Engn, Dept Organ Chem, B-9000 Ghent, Belgium

来源：

TETRAHEDRON | 2010年 / 66卷 / 35期

关键词：

Pyranonaphthoquinones; Pentalongin; Pyridinium ylids; 2 NAPHTHOQUINONE ANTIBIOTICS; METABOLITES; PSYCHORUBRIN; QUINONES;

D O I：

10.1016/j.tet.2010.07.012

中图分类号：

O62 [有机化学];

学科分类号：

070303 [有机化学];

摘要：

3-Substituted pentalongin derivatives possessing an acetal function at C-1 were synthesized by cyclization of acylmethylnaphthoquinones. The latter naphthoquinones were prepared starting from 2-dioxolanylnaphthoquinone by means of both a stoichiometric and a catalytic method deploying various pyridinium ylids. (C) 2010 Elsevier Ltd. All rights reserved.

引用

页码：7088 / 7096

页数：9

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