CASP11 statistics and the prediction center evaluation system

被引：33

作者：

Kryshtafovych, Andriy ^{[1
]}

Monastyrskyy, Bohdan ^{[1
]}

Fidelis, Krzysztof ^{[1
]}

机构：

[1] Univ Calif Davis, Genome & Biomed Sci Facil, Prot Struct Predict Ctr, Davis, CA 95616 USA

来源：

PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS | 2016年 / 84卷

关键词：

CASP; protein structure prediction; protein structure modeling; PROTEIN; MODELS; SCORE;

D O I：

10.1002/prot.25005

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

We outline the role of the Protein Structure Prediction Center (predictioncenter.org) in conducting the CASP11 and CASP ROLL experiments, discuss the experiment statistics, and provide an overview of the present CASP infrastructure. The biggest changes compared to the previous CASPs are the implementation of the evaluation system incorporating practically all evaluation measures, statistical tests, and visualization tools historically used by the CASP assessors, the expansion of the infrastructure to incorporate new categories of contact-assisted and multimeric predictions, and the redesign of the assessors' web-workspace enabling assessments based on multiple measures for different group categories and target sets. (C) 2016 Wiley Periodicals, Inc.

引用

页码：15 / 19

页数：5

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