Imaging basal ganglia function

被引:20
作者
Brooks, DJ [1 ]
机构
[1] Hammersmith Hosp, Imperial Coll Sch Med, MRC, Cyclotron Unit, London W12 0NN, England
关键词
motor control; Parkinson's disease; positron emission tomography;
D O I
10.1046/j.1469-7580.2000.19640543.x
中图分类号
R602 [外科病理学、解剖学]; R32 [人体形态学];
学科分类号
100101 ;
摘要
In this review, the value of functional imaging for providing insight into the role of the basal ganglia in motor control is reviewed. Brain activation findings in normal subjects and Parkinson's disease patients are examined and evidence supporting the existence for functionally independent distributed basal ganglia-frontal loops is presented. It is argued that the basal ganglia probably act to focus and filter cortical output, optimising the running of motor programs.
引用
收藏
页码:543 / 554
页数:12
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