An expedient synthesis of (±)-centrolobine

被引：34

作者：

Clarke, PA ^{[1
]}

Martin, WHC ^{[1
]}

机构：

[1] Univ Nottingham, Sch Chem, Nottingham NG7 2RD, England

来源：

TETRAHEDRON LETTERS | 2004年 / 45卷 / 49期

基金：

英国工程与自然科学研究理事会;

关键词：

centrolobine; tetrahydropyran; one pot; multi-component; Maitland-Japp;

D O I：

10.1016/j.tetlet.2004.10.035

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An expedient synthesis of the antibiotic natural product centrolobine is reported, the key step being the one pot, multicomponent construction of a tetrahydropyran-4-one via a 'revisited' Maitland-Japp reaction. (C) 2004 Elsevier Ltd. All rights reserved.

引用

页码：9061 / 9063

页数：3

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