Serial analysis of gene expression identifies putative metastasis-associated transcripts in colon tumour cell lines

被引：53

作者：

Parle-McDermott, A ^{[1
]}

McWilliam, P ^{[1
]}

Tighe, O ^{[1
]}

Dunican, D ^{[1
]}

Croke, DT ^{[1
]}

机构：

[1] Royal Coll Surg Ireland, Dept Biochem, Dublin 2, Ireland

来源：

BRITISH JOURNAL OF CANCER | 2000年 / 83卷 / 06期

关键词：

SAGE; colon; differential; metastasis; expression;

D O I：

10.1054/bjoc.2000.1330

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

We have used serial analysis of gene expression (SAGE) to identify gene expression differences between a primary colon tumour cell line (SW480) and an isogenic lymph-node metastasis cell line (SW620). Differential expression was confirmed for the following genes: keratin K5, cystatin S, serum amyloid A, the human homologue of yeast ribosomal S28 and the p32 subunit of human pre-mRNA splicing factor SF2. Expression of confirmed differences were also analysed in other metastatic cell lines. (C) 2000 Cancer Research Campaign.

引用

页码：725 / 728

页数：4

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