Bismuth subcarbonate nanoparticles fabricated by water-in-oil microemulsion-assisted hydrothermal process exhibit anti-Helicobacter pylori properties

被引：95

作者：

Chen, Rong ^{[1
,2
,3
,4
]}

Cheng, Gang ^{[1
,2
]}

So, Man Ho ^{[3
,4
]}

Wu, Jiliang ^{[1
,2
]}

Lu, Zhong ^{[1
,2
]}

Che, Chi-Ming ^{[3
,4
]}

Sun, Hongzhe ^{[3
,4
]}

机构：

[1] Wuhan Inst Technol, Key Lab Green Chem Proc, Minist Educ, Wuhan, Peoples R China

[2] Wuhan Inst Technol, Sch Chem Engn & Pharm, Wuhan, Peoples R China

[3] Univ Hong Kong, Dept Chem, Hong Kong, Hong Kong, Peoples R China

[4] Univ Hong Kong, Open Lab Chem Biol, Inst Mol Technol Drug Discovery & Synth, Hong Kong, Hong Kong, Peoples R China

来源：

MATERIALS RESEARCH BULLETIN | 2010年 / 45卷 / 05期

基金：

中国国家自然科学基金;

关键词：

Inorganic compounds; Nanostructures; Electron microscopy; X-ray diffraction; SILICA-SUPPORTED CATALYSTS; SILVER NANOPARTICLES; ANTIBACTERIAL ACTIVITY; OXIDE NANOPARTICLES; METAL; PARTICLES; HYDROLYSIS; OXIDATION; EMULSION; CITRATE;

D O I：

10.1016/j.materresbull.2009.12.035

中图分类号：

T [工业技术];

学科分类号：

120111 [工业工程];

摘要：

Well-crystallized bismuth subcarbonate ((BiO)(2)CO3) nanoparticles were successfully synthesized by water-in-oil (w/o) microemulsion-assisted hydrothermal method. In this synthesis, bismuth citrate and urea are used as the precursors and the thermal decomposition of citrate leads to the formation of major carbonate anion. The reaction, nucleation and growth steps are confined inside the water droplets and hence uniform and well-crystallized spherical nanoparticles are formed. Importantly, these nanoparticles exert comparable anti-Helicobacter pylori activities to the clinically used drug, colloidal bismuth subcitrate (CBS), which offers a promise for development of new nanomedicines. (c) 2010 Elsevier Ltd. All rights reserved.

引用

页码：654 / 658

页数：5

共 36 条

[1]

Synthesis and structural characterisation of CdS nanoparticles prepared in a four-components "water-in-oil" microemulsion [J].