Hydrogels based on pullulan crosslinked with sodium trimetaphosphate (STMP): Rheological study

被引：72

作者：

Lack, S

Dulong, V

Le Cerf, D ^{[1
]}

Picton, L

Argillier, JF

Muller, G

机构：

[1] Univ Rouen, CNRS, UMR 6522, F-76821 Mont St Aignan, France

[2] IFP Energies Nouvelles, F-92852 Rueil Malmaison, France

来源：

POLYMER BULLETIN | 2004年 / 52卷 / 06期

关键词：

pullulan; STMP; polysaccharides; crosslinking; hydrogels;

D O I：

10.1007/s00289-004-0299-4

中图分类号：

O63 [高分子化学（高聚物）];

学科分类号：

070305 ; 080501 ; 081704 ;

摘要：

Hydrogels from pullulan crosslinked with sodium trimetaphosphate (STMP) under alkaline condition have been investigated by rheological measurements. The influence of reagents concentration (pullulan, STMP, NaOH) on kinetics of reaction and rheological properties is reported. Increasing concentrations of any reagents lead to an increase of the crosslinking kinetics. Increasing the polymer concentration leads to a "stronger" gel whereas an increase of crosslinking reagent (STMP) evidences a critical concentration above which the rheological properties of the gel do not change anymore. This may be explained by the specificity of the system for which the polymer concentration is high and negative charges appear.

引用

页码：429 / 436

页数：8

共 20 条

[1] Nano-engineering block copolymer aggregates for drug delivery [J].