Developmental biology - A hairy situation

被引:4
作者
Barrandon, Y [1 ]
机构
[1] Swiss Fed Inst Technol, Sch Life Sci, CH-1011 Lausanne, Switzerland
[2] CHU Vaudois, Dept Expt Surg, CH-1011 Lausanne, Switzerland
关键词
D O I
10.1038/422272a
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
A key step in hair-follicle development is the rearrangement of epithelial stem cells. It seems that reduced production of an adhesion protein, through the concerted action of two signalling pathways, is crucial for this process.
引用
收藏
页码:272 / 273
页数:2
相关论文
共 12 条
[1]   The transcription factor Snail is a repressor of E-cadherin gene expression in epithelial tumour cells [J].
Batlle, E ;
Sancho, E ;
Franci, C ;
Domínguez, D ;
Monfar, M ;
Baulida, J ;
de Herreros, AG .
NATURE CELL BIOLOGY, 2000, 2 (02) :84-89
[2]   Noggin is a mesenchymally derived stimulator of hair-follicle induction [J].
Botchkarev, VA ;
Botchkareva, NV ;
Roth, W ;
Nakamura, M ;
Chen, LH ;
Herzog, W ;
Lindner, G ;
McMahon, JA ;
Peters, C ;
Lauster, R ;
McMahon, AP ;
Paus, R .
NATURE CELL BIOLOGY, 1999, 1 (03) :158-164
[3]   The transcription factor Snail controls epithelial-mesenchymal transitions by repressing E-cadherin expression [J].
Cano, A ;
Pérez-Moreno, MA ;
Rodrigo, I ;
Locascio, A ;
Blanco, MJ ;
del Barrio, MG ;
Portillo, F ;
Nieto, MA .
NATURE CELL BIOLOGY, 2000, 2 (02) :76-83
[4]   Regulation of LEF-1/TCF transcription factors by Wnt and other signals [J].
Eastman, Q ;
Grosschedl, R .
CURRENT OPINION IN CELL BIOLOGY, 1999, 11 (02) :233-240
[5]   Getting under the skin of epidermal morphogenesis [J].
Fuchs, E ;
Raghavan, S .
NATURE REVIEWS GENETICS, 2002, 3 (03) :199-209
[6]   Regulation of cadherin adhesive activity [J].
Gumbiner, BM .
JOURNAL OF CELL BIOLOGY, 2000, 148 (03) :399-403
[7]  
HIRAI Y, 1989, DEVELOPMENT, V105, P271
[8]   β-catenin controls hair follicle morphogenesis and stem cell differentiation in the skin [J].
Huelsken, J ;
Vogel, R ;
Erdmann, B ;
Cotsarelis, G ;
Birchmeier, W .
CELL, 2001, 105 (04) :533-545
[9]   Links between signal transduction, transcription and adhesion in epithelial bud development [J].
Jamora, C ;
DasGupta, R ;
Kocieniewski, P ;
Fuchs, E .
NATURE, 2003, 422 (6929) :317-322
[10]   Sticky business: Orchestrating cellular signals at adherens junctions [J].
Perez-Moreno, M ;
Jamora, C ;
Fuchs, E .
CELL, 2003, 112 (04) :535-548