Splenic rupture in a parental donor undergoing peripheral blood progenitor cell mobilization

被引：34

作者：

Dincer, AP

Gottschall, J

Margolis, DA

机构：

[1] Med Coll Wisconsin, Div Neoplast Dis & Related Disorders, Dept Med, Milwaukee, WI 53226 USA

[2] Med Coll Wisconsin, Dept Pediat, Milwaukee, WI 53226 USA

来源：

JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY | 2004年 / 26卷 / 11期

关键词：

granulocyte colony-stimulating factor; stem cell mobilization; splenic rupture;

D O I：

10.1097/00043426-200411000-00015

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Peripheral blood progenitor cells (PBPCs) are now widely used as a source of progenitor cells for allogeneic transplantation. Recombinant human granulocyte colony-stimulating factor is used to mobilize PBPCs for collection by leukapheresis. Although side effects of mobilization are generally benign, adverse effects have been reported. The authors present a case of spontaneous splenic rupture, without splenomegaly, in a parental donor undergoing PBPC mobilization, review the literature regarding this adverse event, and explore issues regarding donor safety.

引用

收藏

页码：761 / 763

页数：3

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