The Clopidogrel in Unstable Angina to Prevent Recurrent Events (CURE) study: To what extent should the results be generalizable?

被引:28
作者
Gerschutz, GP [1 ]
Bhatt, DL [1 ]
机构
[1] Cleveland Clin Fdn, Dept Cardiol, Cleveland, OH 44195 USA
关键词
D O I
10.1067/mhj.2003.180
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
The Clopidogrel in Unstable Angina to Prevent Recurrent Events (CURE) study investigated the use of clopidogrel in the treatment of acute coronary syndromes. Clopidogrel treatment led to an impressive 20% relative risk reduction in the composite outcome measure of vascular death, myocardial infarction, and stroke. Increased bleeding and greater requirements for blood transfusions were seen with clopidogrel. The addition-of clopidogrel to aspirin represents a major advance in the treatment of acute coronary syndromes.
引用
收藏
页码:595 / 601
页数:7
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