Transcriptional Control of Brown Fat Development

被引：326

作者：

Kajimura, Shingo ^{[1
,2
]}

Seale, Patrick ^{[3
]}

Spiegelman, Bruce M. ^{[1
,2
]}

机构：

[1] Harvard Univ, Sch Med, Dana Farber Canc Inst, Boston, MA 02115 USA

[2] Harvard Univ, Sch Med, Dept Cell Biol, Boston, MA 02115 USA

[3] Univ Penn, Sch Med, Inst Diabet Obes & Metab, Philadelphia, PA 19104 USA

来源：

CELL METABOLISM | 2010年 / 11卷 / 04期

关键词：

ADIPOSE-TISSUE; WHITE FAT; ADULT HUMANS; PGC-1-ALPHA; GENE; DIFFERENTIATION; ADIPOCYTES; SWITCH; ADIPOGENESIS; EXPRESSION;

D O I：

10.1016/j.cmet.2010.03.005

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Deconvoluting the natural pathway of BAT development has defined key molecular events, which enables researchers to manipulate the amount or activity of brown fat. We review recent advances on the transcriptional regulation of BAT development and discuss the emerging questions.

引用

页码：257 / 262

页数：6

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