Conjunctival melanoma

被引:165
作者
Seregard, S
机构
[1] St Eriks Eye Hosp, Ophthalm Pathol & Oncol Serv, S-11282 Stockholm, Sweden
[2] Karolinska Inst, Stockholm, Sweden
关键词
conjunctival melanoma; malignancy; melanoma; prognostic factors; tumor;
D O I
10.1016/S0039-6257(97)00122-7
中图分类号
R77 [眼科学];
学科分类号
100212 ;
摘要
Conjunctival melanoma is an uncommon tumor that is likely to recur and carries an overall mortality rate of approximately 30%. The seemingly unpredictable and enigmatic character of this entity has initiated much debate over the past decades regarding the etiology, histogenesis, prognosis, and preferred management. This review outlines the historical perspective; incidence and demographics; etiologic factors; histogenesis; cytogenetic findings; clinical characteristics; histopathologic and ultrastructural features; differential diagnoses; classifications; management of primary, recurrent, and systemic disease; survival after conjunctival melanoma; and diverse factors of potential prognostic significance. Finally, a brief outlook on present and future research objectives is provided. (C) 1998 by Elsevier Science Inc. All rights reserved.).
引用
收藏
页码:321 / 350
页数:30
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