Crude drugs from aquatic plants. VII. Four new thiaspirane sulfoxide type nuphar alkaloids, nupharpumilamines A, B, C, and D, from Chinese Nupharis rhizoma, the rhizoma of Nuphar pumilum (Timm.) DC. (Nymphaceae)

被引：11

作者：

Yoshikawa, M ^{[1
]}

Murakami, T ^{[1
]}

Ishikado, A ^{[1
]}

Wakao, S ^{[1
]}

Murakami, N ^{[1
]}

Yamahara, J ^{[1
]}

Matsuda, H ^{[1
]}

机构：

[1] Kyoto Pharmaceut Univ, Yamashima Ku, Kyoto 607, Japan

来源：

HETEROCYCLES | 1997年 / 46卷

关键词：

D O I：

10.3987/COM-97-S15

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Following the characterization of thiohemiaminal type nuphar alkaloids with immunosuppressive activity, four new thiaspirane sulfoxide type dimeric sesquiterpene alkaloids, nupharpumilamines A, B, C, and D, were isolated from Chinese Nupharis Rhizoma, the dried rhizoma of Nuphar pumilum (TIMM.) DC. The structures of nupharpumilamines A, B, C, and D were determined on the basis of chemical and physicochemical evidence.

引用

页码：301 / 308

页数：8

共 21 条

[1] ZUR KONFIGURATIONSBESTIMMUNG VON CHINOLIZIN-DERIVATEN [J].

BOHLMANN, F .

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 1957, 69 (20) :641-642

[2] SULFOXIDES OF THIOBINUPHARIDINE THIOHEMIAMINALS FROM NUPHAR-LUTEA [J].

IWANOW, A ;

WOJTASIEWICZ, K ;

WROBEL, JT .

PHYTOCHEMISTRY, 1986, 25 (09) :2227-2231

[3]

LALONDE R, 1970, TETRAHEDRON LETT, V51, P4477

[4] NEW MONOHEMIAMINAL DERIVATIVES OF THIOBINUPHARIDINE AND THIONUPHLUTINE-B - ROLE OF CIRCULAR-DICHROISM AND MASS-SPECTROMETRY IN ASCERTAINING POSITION OF HEMIAMINAL FUNCTION [J].

LALONDE, RT ;

WONG, CF ;

DAS, KC .

JOURNAL OF ORGANIC CHEMISTRY, 1974, 39 (19) :2892-2897

[5] ELECTRON-IMPACT MASS-SPECTROMETRY OF NUPHAR ALKALOIDS .2. THIOHEMIAMINALS [J].

LALONDE, RT ;

WONG, C ;

TSAI, AIM .

ORGANIC MASS SPECTROMETRY, 1976, 11 (02) :183-187

[6] STEREOSPECIFICITY OF ALPHA-THIOHEMIAMINAL REDUCTION - 300 MHZ PROTON MAGNETIC-RESONANCE INVESTIGATION OF DEUTERIDE REDUCTION PRODUCTS FROM 6,6'-DIHYDROXYTHIOBINUPHARIDINE AND 6-HYDROXYTHIOBINUPHARIDINE [J].

LALONDE, RT ;

WONG, CF ;

DAS, KC .

CANADIAN JOURNAL OF CHEMISTRY-REVUE CANADIENNE DE CHIMIE, 1974, 52 (15) :2714-2716

[7]

LALONDE RT, 1976, CAN J CHEM, V54, P3861

[8] HYDRIDE REDUCTION OF HEMIAMINALS OF THIOBINUPHARIDINE AND STRUCTURE OF THIONUPHAROLINE [J].

MARTIN, TI ;

MACLEAN, DB ;

WROBEL, JT ;

IWANOW, A ;

STARZEC, W .

CANADIAN JOURNAL OF CHEMISTRY-REVUE CANADIENNE DE CHIMIE, 1974, 52 (15) :2705-2713

[9] STRUCTURE OF LANTHANIDE COMPLEXES WITH 5-MEMBERED SULFONES AND SPECIFIC BENZENE SOLVATION [J].

WROBEL, JT ;

KABZINSKA, K ;

RUSZKOWSKA, J ;

WRONA, PK .

JOURNAL OF MOLECULAR STRUCTURE, 1977, 41 (02) :287-298

[10]

WROBEL JT, 1976, B ACAD POL SCI-CHIM, V24, P99

← 1 2 3 →