Crude drugs from aquatic plants. VII. Four new thiaspirane sulfoxide type nuphar alkaloids, nupharpumilamines A, B, C, and D, from Chinese Nupharis rhizoma, the rhizoma of Nuphar pumilum (Timm.) DC. (Nymphaceae)

被引：11

作者：

Yoshikawa, M ^{[1
]}

Murakami, T ^{[1
]}

Ishikado, A ^{[1
]}

Wakao, S ^{[1
]}

Murakami, N ^{[1
]}

Yamahara, J ^{[1
]}

Matsuda, H ^{[1
]}

机构：

[1] Kyoto Pharmaceut Univ, Yamashima Ku, Kyoto 607, Japan

来源：

HETEROCYCLES | 1997年 / 46卷

关键词：

D O I：

10.3987/COM-97-S15

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Following the characterization of thiohemiaminal type nuphar alkaloids with immunosuppressive activity, four new thiaspirane sulfoxide type dimeric sesquiterpene alkaloids, nupharpumilamines A, B, C, and D, were isolated from Chinese Nupharis Rhizoma, the dried rhizoma of Nuphar pumilum (TIMM.) DC. The structures of nupharpumilamines A, B, C, and D were determined on the basis of chemical and physicochemical evidence.

引用

页码：301 / 308

页数：8