Spread in an Italian hospital of a clonal Acinetobacter baumannii strain producing the TEM-92 extended-spectrum β-lactamase

被引：37

作者：

Endimiani, Andrea

Luzzaro, Francesco

Migliavacca, Roberta

Mantengoli, Elisabetta

Hujer, Andrea M.

Hujer, Kristine M.

Pagani, Laura

Bonomo, Robert A.

Rossolini, Gian Maria

Toniolo, Antonio

机构：

[1] Osped Circolo Varese, Microbiol Lab, I-21100 Varese, Italy

[2] Univ Insubria, I-21100 Varese, Italy

[3] Univ Pavia, Dipartimento Sci Morfol Eidol & Clin, Sez Microbiol, I-27100 Pavia, Italy

[4] Univ Siena, Dipartimento Biol Mol, Sez Microbiol, I-53100 Siena, Italy

[5] Louis Stokes Cleveland Vet Affairs Med Ctr, Res Serv, Cleveland, OH 44106 USA

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2007年 / 51卷 / 06期

关键词：

D O I：

10.1128/AAC.01139-06

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Clinical isolates of Acinetobacter baumannii (n = 470) were collected during a 7-year period and investigated for the genetic determinants of resistance to expanded-spectrum beta-lactams. Thirty-one isolates produced the TEM-92 extended-spectrum beta-lactamase (ESBL) and were clonally related. This is the first report of A. baumannii producing a TEM-type ESBL.

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页码：2211 / 2214

页数：4

相关论文

共 26 条

[1] Mechanisms of multidrug resistance in Acinetobacter species and Pseudomonas aeruginosa [J].

Bonomo, Robert A. ;

Szabo, Dora .

CLINICAL INFECTIOUS DISEASES, 2006, 43 :S49-S56

[2] Investigation of a nosocomial outbreak of extended-spectrum β-lactamase VEB-1-producing isolates of Acinetobacter baumannii in a hospital setting [J].

Carbonne, A ;

Naas, T ;

Blanckaert, K ;

Couzigou, C ;

Cattoen, C ;

Chagnon, JL ;

Nordmann, P ;

Astagneau, P .

JOURNAL OF HOSPITAL INFECTION, 2005, 60 (01) :14-18

[3] Spread of blaCTX-M-type and blaPER-2 β-lactamase genes in clinical isolates from Bolivian hospitals [J].

Celenza, G ;

Pellegrini, C ;

Caccamo, M ;

Segatore, B ;

Amicosante, G ;

Perilli, M .

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2006, 57 (05) :975-978

[4]

*CLIN LAB STAND I, 2006, M100S16 CLSI

[5] New TEM variant (TEM-92) produced by Proteus mirabilis and Providencia stuartii isolates [J].

De Champs, C ;

Monne, C ;

Bonnet, R ;

Sougakoff, W ;

Sirot, D ;

Chanal, C ;

Sirot, J .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2001, 45 (04) :1278-1280

[6] Proteus mirabilis bloodstream infections:: Risk factors and treatment outcome related to the expression of extended-spectrum β-lactamases [J].

Endimiani, A ;

Luzzaro, F ;

Brigante, G ;

Perilli, M ;

Lombardi, G ;

Amicosante, G ;

Rossolini, GM ;

Toniolo, A .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2005, 49 (07) :2598-2605

[7]

Falagas ME, 2006, CRIT CARE, V10, DOI [10.1186/cc4910, 10.1186/cc4869]

[8]

Huang Zhi-mi, 2004, Zhonghua Liu Xing Bing Xue Za Zhi, V25, P425

[9] Identification of a new allelic variant of the Acinetobacter baumannii cephalosporinase, ADC-7 β-lactamase:: Defining a unique family of class C enzymes [J].

Hujer, KM ;

Hamza, NS ;

Hujer, AM ;

Perez, F ;

Helfand, MS ;

Bethel, CR ;

Thomson, JM ;

Anderson, VE ;

Barlow, M ;

Rice, LB ;

Tenover, FC ;

Bonomo, RA .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2005, 49 (07) :2941-2948

[10]

JARLIER V, 1988, REV INFECT DIS, V10, P867