Thromboembolic complications of cancer: Epidemiology, pathogenesis, diagnosis, and treatment

被引:125
作者
Sutherland, DE [1 ]
Weitz, IC [1 ]
Liebman, HA [1 ]
机构
[1] Univ So Calif, Keck Sch Med, Div Hematol, Dept Med, Los Angeles, CA USA
关键词
cancer; thrombosis; pulmonary embolism; chemotherapy;
D O I
10.1002/ajh.10263
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
The association between malignancy and clinical thrombosis has been recognized for nearly 140 years. The purpose of this review is to examine our current understanding of thrombosis as a complication of cancer and cancer therapy. The review includes a discussion of the epidemiology, pathophysiology, diagnosis and treatment. (C) 2002 Wiley-Liss, Inc.
引用
收藏
页码:43 / 52
页数:10
相关论文
共 91 条
[31]   DIFFERENT INTENSITIES OF ORAL ANTICOAGULANT-THERAPY IN THE TREATMENT OF PROXIMAL-VEIN THROMBOSIS [J].
HULL, R ;
HIRSH, J ;
JAY, R ;
CARTER, C ;
ENGLAND, C ;
GENT, M ;
TURPIE, AGG ;
MCLOUGHLIN, D ;
DODD, P ;
THOMAS, M ;
RASKOB, G ;
OCKELFORD, P .
NEW ENGLAND JOURNAL OF MEDICINE, 1982, 307 (27) :1676-1681
[32]   Incidence of recurrent thromboembolic and bleeding complications among patients with venous thromboembolism in relation to both malignancy and achieved international normalized ratio:: A retrospective analysis [J].
Hutten, BA ;
Prins, MH ;
Gent, M ;
Ginsberg, J ;
Tijssen, JGP ;
Büller, HR .
JOURNAL OF CLINICAL ONCOLOGY, 2000, 18 (17) :3078-3083
[33]   Treatment of patients with venous thromboembolism and malignant disease: Should vena cava filter placement be routine? [J].
Ihnat, DM ;
Mills, JL ;
Hughes, JD ;
Gentile, AT ;
Berman, SS ;
Westerband, A .
JOURNAL OF VASCULAR SURGERY, 1998, 28 (05) :800-807
[34]  
Janssen MCH, 1997, THROMB HAEMOSTASIS, V77, P262
[35]   Current strategies for the diagnosis of pulmonary embolus [J].
Johnson, MS .
JOURNAL OF VASCULAR AND INTERVENTIONAL RADIOLOGY, 2002, 13 (01) :13-23
[36]   Prevention of venous thromboembolism in cancer patients [J].
Kakkar, AK ;
Williamson, RCN .
SEMINARS IN THROMBOSIS AND HEMOSTASIS, 1999, 25 (02) :239-243
[37]   The role of venous ultrasonography in the diagnosis of suspected deep venous thrombosis and pulmonary embolism [J].
Kearon, C ;
Ginsberg, JS ;
Hirsh, J .
ANNALS OF INTERNAL MEDICINE, 1998, 129 (12) :1044-1049
[38]   Management of suspected deep venous thrombosis in outpatients by using clinical assessment and D-dimer testing [J].
Kearon, C ;
Ginsberg, JS ;
Douketis, J ;
Crowther, M ;
Brill-Edwards, P ;
Weitz, JI ;
Hirsh, J .
ANNALS OF INTERNAL MEDICINE, 2001, 135 (02) :108-111
[39]  
KEARON C, 2001, HEMOSTASIS THROMBOSI, P1153
[40]   Plasma D-dimer measurement in patients with suspected DVT - a means of avoiding unnecessary venography [J].
Khaira, HS ;
Mann, J .
EUROPEAN JOURNAL OF VASCULAR AND ENDOVASCULAR SURGERY, 1998, 15 (03) :235-238