Ephrins keep dendritic spines in shape

被引：17

作者：

Thompson, SM ^{[1
]}

机构：

[1] Univ Maryland, Sch Med, Dept Physiol, Baltimore, MD 21201 USA

来源：

NATURE NEUROSCIENCE | 2003年 / 6卷 / 02期

关键词：

D O I：

10.1038/nn0203-103

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

The EphB ephrin receptors are involved in synapse formation. New work now implicates the EphA family, as glial ephrin3A activates the EphA4 receptor on dendritic spines to stabilize spine shape.

引用

页码：103 / 104

页数：2

共 15 条

[1] EphB receptors interact with NMDA receptors and regulate excitatory synapse formation [J].

Dalva, MB ;

Takasu, MA ;

Lin, MZ ;

Shamah, SM ;

Hu, L ;

Gale, NW ;

Greenberg, ME .

CELL, 2000, 103 (06) :945-956

[2] Spine motility with synaptic contact [J].

Dunaevsky, A ;

Blaszeski, R ;

Yuste, R ;

Mason, C .

NATURE NEUROSCIENCE, 2001, 4 (07) :685-686

[3] EphB/syndecan-2 signaling in dendritic spine morphogenesis [J].

Ethell, IM ;

Irie, F ;

Kalo, MS ;

Couchman, JR ;

Pasquale, EB ;

Yamaguchi, Y .

NEURON, 2001, 31 (06) :1001-1013

[4] The ephrins and Eph receptors in neural development [J].

Flanagan, JG ;

Vanderhaeghen, P .

ANNUAL REVIEW OF NEUROSCIENCE, 1998, 21 :309-345

[5] Kinase-independent requirement of EphB2 receptors in hippocampal synaptic plasticity [J].

Grunwald, IC ;

Korte, M ;

Wolfer, D ;

Wilkinson, GA ;

Unsicker, K ;

Lipp, HP ;

Bonhoeffer, T ;

Klein, D .

NEURON, 2001, 32 (06) :1027-1040

[6] The receptor tyrosine kinase EphB2 regulates NMDA-dependent synaptic function [J].

Henderson, JT ;

Georgiou, J ;

Jia, ZP ;

Robertson, J ;

Elowe, S ;

Roder, JC ;

Pawson, T .

NEURON, 2001, 32 (06) :1041-1056

[7] EphB receptors regulate dendritic spine development via intersectin, Cdc42 and N-WASP [J].

Irie, F ;

Yamaguchi, Y .

NATURE NEUROSCIENCE, 2002, 5 (11) :1117-1118

[8] ASTROCYTIC VOLUME FLUCTUATES IN THE HIPPOCAMPAL CA1 REGION ACROSS THE ESTROUS-CYCLE [J].

KLINTSOVA, A ;

LEVY, WB ;

DESMOND, NL .

BRAIN RESEARCH, 1995, 690 (02) :269-274

[9] Control of hippocampal dendritic spine morphology through ephrin-A3/EphA4 signaling [J].

Murai, KK ;

Nguyen, LN ;

Irie, F ;

Yamaguchi, Y ;

Pasquale, EB .

NATURE NEUROSCIENCE, 2003, 6 (02) :153-160

[10] Structure and function of dendritic spines [J].

Nimchinsky, EA ;

Sabatini, BL ;

Svoboda, K .

ANNUAL REVIEW OF PHYSIOLOGY, 2002, 64 :313-353

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