Development of a vaccine for toxoplasmosis: current status

被引：104

作者：

Bhopale, GM ^{[1
]}

机构：

[1] Hindustan Antibiot Ltd, Div Res & Dev, Parasitol & Immunodiagnost Lab, Pune 411018, Maharashtra, India

来源：

MICROBES AND INFECTION | 2003年 / 5卷 / 05期

关键词：

toxoplasmosis; vaccine;

D O I：

10.1016/S1286-4579(03)00048-0

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The need for a vaccine for human toxoplasmosis is briefly discussed. Recent progress in knowledge of the protective immune response generated by Toxoplasma gondii and the current status of development of a vaccine for toxoplasmosis are highlighted. (C) 2003 Editions scientifiques et medicales Elsevier SAS. All rights reserved.

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收藏

页码：457 / 462

页数：6

相关论文

共 59 条

[1]

ADAMS LB, 1990, J IMMUNOL, V144, P2725

[2] Immunization with a DNA plasmid encoding the SAG1 (P30) protein of Toxoplasma gondii is immunogenic and protective in rodents [J].

Angus, CW ;

Klivington-Evans, D ;

Dubey, JP ;

Kovacs, JA .

JOURNAL OF INFECTIOUS DISEASES, 2000, 181 (01) :317-324

[3] IMMUNIZATION AGAINST TOXOPLASMA-GONDII [J].

ARAUJO, FG .

PARASITOLOGY TODAY, 1994, 10 (09) :358-360

[4] Assessment of enzyme linked immunosorbent assay based diagnostic kits (Toxokit-G and Toxokit-M) for the detection of IgG and IgM antibodies to Toxoplasma gondii in human serum [J].

Bhopale, GM ;

Naik, SR ;

Bhave, GG ;

Naik, SS ;

Gogate, A .

COMPARATIVE IMMUNOLOGY MICROBIOLOGY AND INFECTIOUS DISEASES, 1997, 20 (04) :309-314

[5] INDUCTION OF BRADYZOITE-SPECIFIC TOXOPLASMA-GONDII ANTIGENS IN GAMMA-INTERFERON-TREATED MOUSE MACROPHAGES [J].

BOHNE, W ;

HEESEMANN, J ;

GROSS, U .

INFECTION AND IMMUNITY, 1993, 61 (03) :1141-1145

[6] REDUCED REPLICATION OF TOXOPLASMA-GONDII IS NECESSARY FOR INDUCTION OF BRADYZOITE-SPECIFIC ANTIGENS - A POSSIBLE ROLE FOR NITRIC-OXIDE IN TRIGGERING STAGE CONVERSION [J].

BOHNE, W ;

HEESEMANN, J ;

GROSS, U .

INFECTION AND IMMUNITY, 1994, 62 (05) :1761-1767

[7] Intranasal immunization with SAG1 and nontoxic mutant heat-labile enterotoxins protects mice against Toxoplasma gondii [J].

Bonenfant, C ;

Dimier-Poisson, I ;

Velge-Roussel, F ;

Buzoni-Gatel, D ;

Del Giudice, G ;

Rappuoli, R ;

Bout, D .

INFECTION AND IMMUNITY, 2001, 69 (03) :1605-1612

[8] ORAL IMMUNIZATION WITH TOXOPLASMA-GONDII ANTIGENS IN ASSOCIATION WITH CHOLERA-TOXIN INDUCES ENHANCED PROTECTIVE AND CELL-MEDIATED-IMMUNITY IN C57BL/6 MICE [J].

BOURGUIN, I ;

CHARDES, T ;

BOUT, D .

INFECTION AND IMMUNITY, 1993, 61 (05) :2082-2088

[9]

BROWN CR, 1995, IMMUNOLOGY, V85, P419

[10]

BULOW R, 1991, J IMMUNOL, V147, P3496

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