Effect of antibiotics on Stahylococcus aureus producing Panton-Valentine leukocidin

被引:144
作者
Dumitrescu, Oana
Boisset, Sandrine
Badiou, Cedric
Bes, Michele
Benito, Yvonne
Reverdy, Marie-Elisabeth
Vandenesch, Francois
Etienne, Jerome
Lina, Gerard
机构
[1] Ctr Natl Reference Staphylocoques, INSERM EO230, F-69372 Lyon 08, France
[2] INSERM, F-69008 Lyon, France
关键词
D O I
10.1128/AAC.01201-06
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
We examined the capacity of Staphylococcus aureus strains to release Panton-Valentine leukocidin (PVL) in the presence of antibiotics. No PVL was detected when S. aureus was incubated at inhibitory concentrations, while subinhibitory concentrations of oxacillin enhanced the PVL level; clindamycin, linezolid, and fusidic acid were inhibitory; and vancomycin had roughly no effect.
引用
收藏
页码:1515 / 1519
页数:5
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