A Versatile and Scalable Strategy to Discrete Oligomers

被引：119

作者：

Lawrence, Jimmy ^{[1
,2
,3
]}

Lee, Sang-Ho ^{[1
,2
,3
]}

Abdilla, Allison ^{[1
,2
,3
]}

Nothling, Mitchell D. ^{[1
,2
,3
,4
]}

Ren, Jing M. ^{[1
,2
,3
]}

Knight, Abigail S. ^{[1
,2
,3
]}

Fleischmann, Carolin ^{[1
,2
,3
]}

Li, Youli ^{[1
,2
,3
]}

Abrams, Austin S. ^{[1
,2
,3
]}

Schmidt, Bernhard V. K. J. ^{[1
,2
,3
,5
]}

Hawker, Michael C. ^{[1
,2
,3
]}

Connal, Luke A. ^{[4
]}

McGrath, Alaina J. ^{[1
,2
,3
]}

Clark, Paul G. ^{[6
]}

Gutekunst, Will R. ^{[1
,2
,3
]}

Hawker, Craig J. ^{[1
,2
,3
]}

机构：

[1] Univ Calif Santa Barbara, Mat Res Lab, Santa Barbara, CA 93106 USA

[2] Univ Calif Santa Barbara, Dept Mat, Santa Barbara, CA 93106 USA

[3] Univ Calif Santa Barbara, Dept Chem & Biochem, Santa Barbara, CA 93106 USA

[4] Univ Melbourne, Dept Chem Engn, Melbourne, Vic, Australia

[5] Max Planck Inst Colloids & Interfaces, D-14424 Potsdam, Germany

[6] Dow Chem Co USA, Midland, MI 48674 USA

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2016年 / 138卷 / 19期

基金：

美国国家科学基金会;

关键词：

THIN-LAYER-CHROMATOGRAPHY; OPENING METATHESIS POLYMERIZATION; SEQUENCE-CONTROLLED POLYMERS; VINYL COPOLYMERS; BUILDING-BLOCKS; MACROMOLECULES; POLYSTYRENES; DERIVATIVES; ADSORPTION; DENDRIMERS;

D O I：

10.1021/jacs.6b03127

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A versatile strategy is reported for the multigram synthesis of discrete oligomets from commercially available monomer. families, e.g.; acrylates, styrenics, and: siloxanes. Central to this strategy is the identification of reproducible procedures for the separation of oligomer mixtures using automated flash chromatography systems with the effectiveness :of this approach demonstrated through the multigram preparation of discrete oligomer libraries (D = 1.0). Synthetic availability, coupled with accurate, structural control, allows these functional building blocks to be harnessed for both fundamental studies as well as targeted technological applications.

引用

页码：6306 / 6310

页数：5

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