Copper-Mediated Homocoupling of Vinyl Dibromides to Symmetrical Diynes

被引：23

作者：

Coste, Alexis ^{[1
]}

Couty, Francois ^{[1
]}

Evano, Gwilherm ^{[1
]}

机构：

[1] Univ Versailles St Quentin en Yvelines, CNRS, UMR 8180, Inst Lavoisier Versailles, F-78035 Versailles, France

来源：

SYNTHESIS-STUTTGART | 2010年 / 09期

关键词：

dibromoalkenes; copper catalysis; 1,3-diynes; ONE-POT SYNTHESIS; COUPLING REACTIONS; EFFICIENT SYNTHESIS; C-C; 1,1-DIBROMO-1-ALKENES; CYCLIZATION; 1,1-DIBROMOOLEFINS; DERIVATIVES; 1,3-DIYNES; AMIDATION;

D O I：

10.1055/s-0029-1218688

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

1,1-Dibromoalk-1-enes were dimerized readily in the presence of copper iodide, a diamine ligand, and cesium carbonate in DMF to give symmetrical 1,3-diynes. The reaction was found to be selective and rather general, furnishing the corresponding diynes in good yields, even with complex and sensitive dibromides, and provides useful insights into the reactivity of 1,1-dibromoalk-1-enes with copper(I).

引用

页码：1500 / 1504

页数：5

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