An analysis of the effect of age on implantation rates

被引：52

作者：

Spandorfer, SD ^{[1
]}

Chung, PH ^{[1
]}

Kligman, I ^{[1
]}

Liu, HC ^{[1
]}

Davis, OK ^{[1
]}

Rosenwaks, Z ^{[1
]}

机构：

[1] Cornell Univ, Med Ctr, New York Hosp, Ctr Reprod Med & Infertil, New York, NY 10021 USA

来源：

JOURNAL OF ASSISTED REPRODUCTION AND GENETICS | 2000年 / 17卷 / 06期

关键词：

implantation; IVF-ET; maternal age;

D O I：

10.1023/A:1009422725434

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Purpose: To evaluate implantation rate as a function of age. Methods: A total of 1621 consecutive cycles of IVF were evaluated for implantation as a function of age at The New York Hospital/Cornell Medical Center. Results: An overall implantation rate of 23.3% (1328/5691) was found. The implantation rate as a function of age decreased in a nonlinear fashion. Implantation remained constant until the age of 35 and then decreased in a significantly, linear fashion by 2.77% per year (P < 0.001, R-2 = 0.975). A formula to predict implantation rates for a given age was developed: Implantation rate = 119.352 + (9.985 x Age - (0.164 x Age(2))). Conclusions: We have demonstrated that implantation rates remain constant until the age of 35 at which time a linear decrease of 2.77% per year is observed.

引用

页码：303 / 306

页数：4

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